The important role of polysaccharides from a traditional Chinese medicine-Lung Cleansing and Detoxifying Decoction against the COVID-19 pandemic
Identifieur interne : 000093 ( Main/Exploration ); précédent : 000092; suivant : 000094The important role of polysaccharides from a traditional Chinese medicine-Lung Cleansing and Detoxifying Decoction against the COVID-19 pandemic
Auteurs : Peng Cao [République populaire de Chine] ; Sanlan Wu [République populaire de Chine] ; Tingting Wu [République populaire de Chine] ; Yahui Deng [République populaire de Chine] ; Qilin Zhang [République populaire de Chine] ; Kaiping Wang [République populaire de Chine] ; Yu Zhang [République populaire de Chine]Source :
- Carbohydrate Polymers [ 0144-8617 ] ; 2020.
Abstract
COVID-19 has become a Public Health Emergency of International Concern (PHEIC) and a world-wide pandemic. The Lung Cleansing and Detoxifying Decoction has shown definite therapeutic effects on COVID-19 patients. Bioactive polysaccharides in the decoction appear to involve immunomodulatory activity, anti-inflammatory activity, anti-oxidative activity and regulation of gut microbiota balance. Producing COVID-19 vaccines with polysaccharides as the adjuvants is an innovative strategy.
Url:
DOI: 10.1016/j.carbpol.2020.116346
PubMed: NONE
PubMed Central: 7175912
Affiliations:
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Precision Medicine for Critical Illness, Wuhan, 430022, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, 430022</wicri:regionArea><wicri:noRegion>430022</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Qilin" sort="Zhang, Qilin" uniqKey="Zhang Q" first="Qilin" last="Zhang">Qilin Zhang</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea><wicri:noRegion>430022</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff0010">Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, 430022, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, 430022</wicri:regionArea><wicri:noRegion>430022</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Kaiping" sort="Wang, Kaiping" uniqKey="Wang K" first="Kaiping" last="Wang">Kaiping Wang</name><affiliation wicri:level="1"><nlm:aff id="aff0015">School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030</wicri:regionArea><wicri:noRegion>430030</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022</wicri:regionArea><wicri:noRegion>430022</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff0010">Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, 430022, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, 430022</wicri:regionArea><wicri:noRegion>430022</wicri:noRegion></affiliation></author></analytic><series><title level="j">Carbohydrate Polymers</title><idno type="ISSN">0144-8617</idno><idno type="eISSN">1879-1344</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">COVID-19 has become a Public Health Emergency of International Concern (PHEIC) and a world-wide pandemic.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">The Lung Cleansing and Detoxifying Decoction has shown definite therapeutic effects on COVID-19 patients.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Bioactive polysaccharides in the decoction appear to involve immunomodulatory activity, anti-inflammatory activity, anti-oxidative activity and regulation of gut microbiota balance.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">Producing COVID-19 vaccines with polysaccharides as the adjuvants is an innovative strategy.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ahmad, A" uniqKey="Ahmad A">A. 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Li</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Cao, Peng" sort="Cao, Peng" uniqKey="Cao P" first="Peng" last="Cao">Peng Cao</name></noRegion><name sortKey="Cao, Peng" sort="Cao, Peng" uniqKey="Cao P" first="Peng" last="Cao">Peng Cao</name><name sortKey="Deng, Yahui" sort="Deng, Yahui" uniqKey="Deng Y" first="Yahui" last="Deng">Yahui Deng</name><name sortKey="Deng, Yahui" sort="Deng, Yahui" uniqKey="Deng Y" first="Yahui" last="Deng">Yahui Deng</name><name sortKey="Wang, Kaiping" sort="Wang, Kaiping" uniqKey="Wang K" first="Kaiping" last="Wang">Kaiping Wang</name><name sortKey="Wu, Sanlan" sort="Wu, Sanlan" uniqKey="Wu S" first="Sanlan" last="Wu">Sanlan Wu</name><name sortKey="Wu, Sanlan" sort="Wu, Sanlan" uniqKey="Wu S" first="Sanlan" last="Wu">Sanlan Wu</name><name sortKey="Wu, Tingting" sort="Wu, Tingting" uniqKey="Wu T" first="Tingting" last="Wu">Tingting Wu</name><name sortKey="Wu, Tingting" sort="Wu, Tingting" uniqKey="Wu T" first="Tingting" last="Wu">Tingting Wu</name><name sortKey="Zhang, Qilin" sort="Zhang, Qilin" uniqKey="Zhang Q" first="Qilin" last="Zhang">Qilin Zhang</name><name sortKey="Zhang, Qilin" sort="Zhang, Qilin" uniqKey="Zhang Q" first="Qilin" last="Zhang">Qilin Zhang</name><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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